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_92.webp "A mum-to-be was diagnosed with cancer at five months pregnant - when her extreme morning sickness turned out to be a symptom of the disease. <br/><br/>Caitlin McAlinden, 24, put her cancer symptoms - including a golf ball-sized lump on her neck, nausea and fatigue - down to morning sickness.<br/><br/>But after losing two stone in four months she was referred to a haematology team at Arrowe Park, the Wirral. <br/><br/>They gave her a neck biopsy and diagnosed her with stage one Hodgkin lymphoma in March 2024. <br/><br/>Caitlin is expected to make a full recovery but has to take a steroid injection and a blood-thinning pill every morning. <br/><br/>After her baby boy is born, on May 8, she’ll start a four-week course of chemotherapy. <br/><br/>Caitlin, a primary school teacher, from Wirral, Merseyside, said: “This isn’t the pregnancy I was hoping for - I haven’t felt well this entire time. <br/><br/>“Everything I want to do after my baby is born has to be put on pause due to the chemo. <br/><br/>“My odds are really good - but having my baby will be a good distraction for everything I’m going through.”<br/><br/>Caitlin found out she was pregnant on September 16, 2023 - after feeling nauseous at her birthday dinner the week before. <br/><br/>Her first trimester was “rocky” and she originally believed she had a severe form of morning sickness.<br/><br/>She was vomiting at least once a day and would fall asleep intermittently throughout the day. <br/><br/>But it wasn’t until Christmas Day that she first noticed the pain in her neck and after weighing herself, noticed she’d lost two stone. <br/><br/>She said: “I went back to County Armagh to visit my family for Christmas. <br/><br/>“I remember Christmas Day, falling asleep on the sofa and waking up with a really sore neck. <br/><br/>“I thought I’d just slept funny, but I started massaging my neck.<br/><br/>“That’s when I found a lump, about the size of a pea.”<br/><br/>Caitlin didn’t want to see a GP at first - believing the lump was just another “weird” sign of pregnancy. <br/><br/>But in just a week, her tiredness became worse and the pea-size lump tripled in size.<br/><br/>“I was so, so tired,” she said. <br/><br/>“Walking up the stairs alone would make me need to go for a lie down.<br/><br/>“I felt my neck again one day and the lump had become golf ball-sized.”<br/><br/>Her partner, Connor, 27, a procurement manager, told Caitlin she needed to see a doctor as soon as possible. <br/><br/>She visited her GP on January 2 and was referred for an initial ultrasound on her neck. <br/><br/>They gave her a biopsy on January 16 and the clinician asked Caitlin if she had any family history of Hodgkin lymphoma. <br/><br/>She told them one of her second cousins had gone through it years before and they urgently sent her for more blood tests. <br/><br/>“My doctor’s whole demeanour changed when I said I had a family history of it,” Caitlin said. <br/><br/>“I went for a blood test on the same day.”<br/><br/>Caitlin was diagnosed with stage one Hodgkin lymphoma on March 12, 2024, and instantly started steroid treatment to shrink the mass on her neck.")
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![Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'](https://cdn1.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KAxb3EmSwAJgZpx13nJ9-FF9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_newly-discovered-gene-variant-could-help-prevent-or-treat-alzheimer39s-disease.webp "Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'")
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