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⏲ Duration: 1 min 20 sec
✓ Published: 16-Mar-2020
✓ Published: 16-Mar-2020
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The Hedgehog signalling pathway plays an important role in embryonic development. (1)nDeregulation of the Hh signalling pathway is associated with developmental abnormalities and cancer including Gorlins Syndrome and sporadic cancer such as BCC.(2)BCC is the most common type of cancer in humans. (1)nThe Hh pathway is mostly inactive in adults but can be turned on when needed, eg, in wound healing (2)nThree proteins are involved in Hh signalling activation: Hedgehog ligand (Hh), Patched (Pt
The Hedgehog signalling pathway plays an important role in embryonic development. (1)nDeregulation of the Hh signalling pathway is associated with developmental abnormalities and cancer including Gorlins Syndrome and sporadic cancer such as BCC.(2)BCC is the most common type of cancer in humans. (1)nThe Hh pathway is mostly inactive in adults but can be turned on when needed, eg, in wound healing (2)nThree proteins are involved in Hh signalling activation: Hedgehog ligand (Hh), Patched (Pt
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