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Beautiful Naat - Shahbaz Qamar Fareedi -
⏲ 4:34 👁 15K
Roma and Diana learn the alphabet ABC song
⏲ 13 minutes 26 seconds 👁 594.4M
Aa Gaya Aa Gaya ( Dance Video ) | Hum Tumhare Hain Sanam | Cover By Kumar Avijit
⏲ 5 minutes 38 seconds 👁 2.4M
Watch yugioh vrians season 1 for free link in description
⏲ 3:2 👁 10K
How to write Bangla Alphabet |' অ ' অজগর আসছে তেড়ে | অ, আ ,ই , ঈ |Aye Ajagar | bornomala Writing
⏲ 17 minutes 26 seconds 👁 384.5K
LYRICAL: Kaise Mujhe | Ghajini | Aamir Khan, Asin | Benny Dayal, Shreya Ghosal | A.R. Rahman
⏲ 6 minutes 3 seconds 👁 68M
Proud be father
⏲ 0:16 👁 10K
Kaise Muhje - shreya ghoshal version only
⏲ 2 minutes 56 seconds 👁 844.2K
Raja ji Baja baji ki na baji HD video Dj Krishna bichhiya
⏲ 6 minutes 49 seconds 👁 2.8M
How Your Body Metabolizes Medications
⏲ 1:42 👁 10K
Rashmika Dance Moves | Saami Saami (Tamil) |#AlluArjun |#Pushpa |#Rashmika |#Sukumar |#DSP
⏲ 12 seconds 👁 8.3M
Banana 2!! (4k memes)
⏲ 18 seconds 👁 57.1M
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_beautiful-naat-shahbaz-qamar-fareedi.webp "#bismillahProduction #<br/>Label - BISMILLAH PRODUCTOIN<br/><br/>Contact Channel No. : +92 321 8851272<br/><br/><br/>Umeed karta hu ye video aap ko pasand aye gi, LIKE kren aur doston ke sath zrur SHARE kren. <br/><br/>#Bismillah_Production<br/><br/>------------------------------------------------------<br/><br/>DISCLAIMER: This Channel DOES NOT Promote or encourage Any illegal activities , all contents provided by This Channel is meant for EDUCATIONAL PURPOSE only .<br/><br/><br/><br/>Please like - subscribe and Share.")
_roma-and-diana-learn-the-alphabet-abc-song.webp "★ Kids Roma Show")
_aa-gaya-aa-gaya-dance-video-124-hum-tumhare-hain-sanam-124-cover-by-kumar-avijit.webp "Jhankar Studio")
_watch-yugioh-vrians-season-1-for-free-link-in-description.webp "If you are interested in watching yugioh vrians season 1 for free then<br/>Click here: https://clk.wiki/Yugioh<br/>About anime:<br/>The Yu-Gi-Oh! universe expands with this story about a hero who battles hackers in cyberspace in private while appearing to be a quiet high schooler.<br/>Starring:Jake PaqueEmily CarmerDaniel J. EdwardsDanny KramerMark Schenfisch<br/>Directed by:Cameron Sharp<br/>If you are interested in watching new intresting anime and movies then follow this channel<br/>")
_how-to-write-bangla-alphabet-12439-39-124-124aye-ajagar-124-bornomala-writing.webp "Mom's Talk : বাংলা")
_lyrical-kaise-mujhe-124-ghajini-124-aamir-khan-asin-124-benny-dayal-shreya-ghosal-124-a-r-rahman.webp "T-Series")
_proud-be-father.webp "Har tara ki videos upload hon gi please like share videos")
_kaise-muhje-shreya-ghoshal-version-only.webp "muffey6")
_raja-ji-baja-baji-ki-na-baji-hd-video-dj-krishna-bichhiya.webp "Dj krishna Bichhiya")
![MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>](https://cdn4.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KHT5GpGSwGmSZZGNkLmObrP9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_how-your-body-metabolizes-medications.webp "MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>")
_rashmika-dance-moves-124-saami-saami-tamil-124alluarjun-124pushpa-124rashmika-124sukumar-124dsp.webp "Aditya Music")
_banana-2-4k-memes.webp "Rico Animations")
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