olaparib prostate cancer Videos

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Prof Rana McKay (The University of California, San Diego, USA), Prof Gunhild von Amsberg (Martini Clinic, Hamburg, Germany) and Dr Friederike Schlurmann (Centre Hospitalier Universitaire de Brest, Brest, France) discuss the latest in PARP inhibitors in prostate cancer. nnThe panel analyses the secondary datasets from trials such as PROPEL 2, TALAPRO 2 and MAGNITUDE and discuss how it impacts our understanding of best practice with the use of PARP inhibitors in prostate cancer. nnThey cover the r
⏲ 10 min 40 sec ✓ 06-Jun-2023
Prostate Cancer Research Institute
⏲ 3 minutes 30 seconds 👁 915
NEJM Group
⏲ 1 minute 33 seconds 👁 883
Dr Neal Shore is joined by Dr Simon Chowdhury, Prof Matthew Smith and Prof Boris Hadaschik at the ASCO 2018 conference in Chicago.nnThe discussion opens with comments on the day's poster sessions here at ASCO 2018, including genomic profiling of tumours from mCRPC patients, which gives promising findings. nnFollowing this there is a discussion about the P3 SPARTAN trial, investigating Association of metastasis-free survival (MFS) and overall survival (OS) in nonmetastatic castration-resistant pr
⏲ 11 min 34 sec ✓ 04-Jun-2018
VJOncology
⏲ 1 minute 15 seconds 👁 40
VJOncology
⏲ 1 minute 19 seconds 👁 70
Dr Grace A Martin speaks about the use of the PARP inhibitor olaparib for the treatment of metastatic castration-resistant prostate cancer.nnDr Martin provides a background on the use of PARP inhibitors in prostate cancer, explaining why there is a need to find a targeted treatment for these patients. She discusses some of the existing research in this area and reports on recent FDA approvals of PARP inhibitors for the treatment of prostate cancer. nnDr Martin describes her own clinical experien
⏲ 4 min 33 sec ✓ 27-Jul-2020
Prof Nick James (University of Birmingham, Birmingham, UK) and Prof Nicholas Mottet (University Hospital St Etienne, St Etienne, France) present the latest developments in metastatic prostate cancer. nnProf Mottet outlines the latest EAU guidelines, including the grouping of patients according to volume of disease and the difference between low-volume and high-volume patients.nnProf James also provides an update on the STAMPEDE trial, and comments on the allocation of patients - who were not gro
⏲ 9 min 18 sec ✓ 29-Sep-2019
Prof Eleni Efstathiou (Houston Methodist Cancer Center, Houston, USA), Prof Boris Hadaschik (University of Duisburg-Essen, Essen, Germany) and Prof Gerhardt Attard (University College London: Cancer Institute, London, UK) discuss the updates in prostate cancer from ESMO 2022.nnThey start by discussing the STAMPEDE trial. They then talk about the biomarker analysis and updated results from the phase III PROpel trial of abiraterone and olaparib versus abiraterone and placebo as first-line therapy
⏲ 15 min 30 sec ✓ 12-Sep-2022
Prof Maha Hussain presents data from thePROfound trial during a press conference at the 2019 ESMO congress.nnThis was a trial evaluating the PARP inhibitor olaparib vs new hormonal agents in patients with metastatic, pre-treated prostate cancer whose cancer cells had faulty DNA repair genes.nnSign up to ecancer for free to receive tailored email alerts for more videos like this.necancer.org/account/register.php
⏲ 5 min 38 sec ✓ 30-Sep-2019
The group discuss a series of phase II trials, predictive biomarkers and signpost emerging therapies from the congress.The discussion begins with reference to a Scandinavian adjuvant study (SPCG-13). Which was a randomised phase III trial between adjuvant docetaxel and surveillance after radical radiotherapy for intermediate and high risk prostate cancer. The group comments that the trial was negative and did not improve BDFS.nThe panel also highlight the continued data from LATITUDE where a d
⏲ 13 min 56 sec ✓ 05-Jun-2018
Prof Karim Fizazi (Institut Gustave Roussy, Paris, France) chairs a session with Dr Joaquin Mateo (Vall d’Hebron Institute of Oncology, Barcelona, Spain), Dr Shahneen Sandhu (Peter MacCallum Cancer, Melbourne, Australia) and Prof Bertrand Tombal (Université catholique de Louvain, Brussels, Belgium) on the key developments in prostate cancer that were presented at ESMO 2019. nnProf Tombal provides a summary of the RADICALS trial which investigated the role of radiation therapy in patients with
⏲ 14 min 47 sec ✓ 02-Oct-2019
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