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Atezolizumab (Tecentriq®) targets the ligand PD-L1 to restore antitumor T-cell activity. Its mechanism of action has three distinct characteristics: direct, complete, and selective. 1) Direct – Atezolizumab targets PD-L1 on tumor cells and tumor-infiltrating immune cells to reactivate T-cells; 2) Complete – Atezolizumab provides dual blockade of PD-1 and B7.1, which can reinvigorate suppressed T-cells to kill cancer cells (via PD-1) and can enhance T-cell priming in the lymph node (via B7.1

Tecentriq Mechanism of Action Video

⏲ 2 min 57 sec ✓ 20-Nov-2018

Living Beyond Breast Cancer

Tecentriq: Tips for continuing treatment when it’s working for you, with Gina M. Spradling

⏲ 13 minutes 2 seconds 👁 387

Ivanhoe Web

NEW IMMUNOTHERAPY TREATMENT FOR LUNG CANCER: TECENTRIQ

⏲ 1 minute 1 second 👁 944

TECENTRIQ from tecentriq

⏲ 57 sec ✓ 05-Jul-2016

curetoday

Tecentriq Approval in NSCLC ‘Stops the Brakes’ on PD-L1 Expression

⏲ 1 minute 35 seconds 👁 457

OncLiveTV

Atezolizumab Versus Other Immunotherapy Options

⏲ 1 minute 18 seconds 👁 2.4K

Tecentriq 8 de abril from tecentriq

Tecentriq 8 de abril

⏲ 43 min 7 sec ✓ 07-Apr-2021

Roche

Cancer immunotherapy | The PD-L1 pathway

⏲ 2 minutes 12 seconds 👁 93K

You and Lung Cancer

Immunotherapy Treatments for Non-Small Cell Lung Cancer (NSCLC)

⏲ 3 minutes 30 seconds 👁 23.2K

LANZAMIENTO ALENCENSA TECENTRIQ

⏲ 1 min 23 sec ✓ 04-Oct-2017

medXclusive Learning

Tecentriq (atezolizumab) approved to treat Advanced Bladder Cancer

⏲ 1 minute 32 seconds 👁 2.5K

TODAY

Cancer Disappears In All Patients During Immunotherapy Drug Trial

⏲ 2 minutes 56 seconds 👁 434.3K

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